Helical powers real scientific outcomes, driving more early discovery breakthroughs in fewer experiments.
Where Bi0 Foundation Models Become In-Silico Labs.
Helical powers in-silico labs across pharma R&D
Helical powers in-silico labs across pharma R&D
- built on DNA, RNA, and single-cell Foundation Models.
- built on DNA, RNA, and single-cell Foundation Models.
Teams run large-scale virtual experiments
Teams run large-scale virtual experiments
from target identification to drug repurposing.
from target identification to drug repurposing.
Helical is the missing link between Bio Foundation Models and lab-grade scientific discovery. Data, models, and in-silico experiments live in one seamless environment.
Pre-trained DNA, RNA, and single-cell Bio FMs, ready to deploy for any experiment.
Integrate your own datasets to specialize models on your biology.
Design and run large-scale in-silico perturbations, biomarker screens, and target ID workflows.
Every experiment is traced - reproducible, regulatory-grade, and scalable.
Start In-Silico Today.
We work selectively with pharma, biotech, and translational research teams exploring Bio Foundation Models for in-silico discoveries.
Early discovery is slowed by unnecessary wet-lab work. Helical reveals what truly deserves your experimental time.
Scale in-silico exploration and advance only the most promising science.
Identification
Run virtual gene perturbations across patient and single-cell data to identify causal drivers and prioritize druggable targets.
Discovery
Harness gene network embeddings from foundation models to identify mechanistic biomarkers and predict therapeutic response.
Repurposing
Leverage drug perturbation simulations with foundation models to reveal new indications with strong mechanistic rationale.
Stratification
Cluster patients by predicted perturbation response to uncover subgroups with shared molecular drivers; informing indication selection and precision trials.
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Identification
Identify and prioritize molecular, cellular and genetic targets with the highest potential for therapeutic intervention, focusing on druggable targets that can transform disease outcomes.
Discovery
Discover molecular indicators that can predict disease progression, treatment response, and patient outcomes using bio-foundation models in Helical's advanced workflows.
Sequence Design
Design and optimise synthetic mRNA constructs for your mRNA therapeutics enhancing stability, translation efficiency, and therapeutic potential across diverse applications.
Stratification
Categorize patients into distinct subgroups based on clinical, molecular, or genetic characteristics to improve therapeutic outcomes and optimise clinical trial design.
Design
Optimise your gene therapy construct through advanced foundation models, refining sequence design to to meet your specific therapeutic goals and desired properties.
Others
Schedule a call with the Helical team to talk about your data. Leverage Helical's platform to build your own use cases and optimize performance with Bio Foundation Models at their core.
We’re a talent-dense team building a generation-defining company from Europe. We seek people who care deeply about the intersection of Bio x AI.
For in-depth community discussions about the latest Bio foundation models and how to use them.
Only for updates about new foundation models and the
latest scientific breakthrough in AI for Bio.
